People who have type 2 diabetes, cardiovascular disease, and depression have a higher risk of all-cause mortality, according to a Washington School of Medicine study. More than 2,000 participants in the Action to Control Cardiovascular Risk in Diabetes study filled out a Patient Health Questionnaire-9, which measures depression symptoms, to help researchers investigate the impact of depression on patients with type 2 diabetes and cardiovascular disease. They found that mortality from all causes was significantly increased for those participants the questionnaire identified as suffering from probable major depression, independent of previous cardiovascular events. "Depression increases the risk of all-cause mortality and may increase the risk of macrovascular events among adults with type 2 diabetes at high risk for cardiovascular events," say the study authors.