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insulin u-500 VS insulin u-100

  • Anonymous ORIGINAL POSTER
    I have heard the name insulin u-500. What is the difference between u-100 and u- 500? Is u-500 insulin better?
  • Samuel Grossman, BS Pharm, Pharm.D, CDE PROFESSIONAL
    Regular insulin u-500 is 5 times more potent than the Regular insulin u-100 that is dispensed in pharmacies. U-500 is not better or worst than u-100, it is just a different kind of insulin. Some patients may benefit from a u-500 insulin, especially individuals with significant insulin resistance. The onset of action of Regular insulin U-500 insulin is similar to Regular insulin U-100. However, the duration of action of u-500 insulin is longer than insulin u-100.